Takotsubo cardiomyopathy is also known as stress cardiomyopathy or broken heart syndrome. When the octopus enters the takotsubo it is most often trapped while the fisherman pulls the device to. Takotsubo syndrome in a premenopausal patient bmj case. Takotsubo cardiomyopathy, also known as transient apical ballooning syndrome, 1 apical ballooning cardiomyopathy, 2 stressinduced cardiomyopathy, brokenheartsyndrome, and simply stress cardiomyopathy, is a type of nonischemic cardiomyopathy in which there is a sudden temporary weakening of the myocardium the muscle of the heart. It is also called stress cardiomyopathy, apical ballooning syndrome, or broken heart syndrome.
Atypical variants of this syndrome with midventricular, basal, and focal wall motion patterns are increasingly diagnosed and show different clinical features compared to typical tts. Broken heart syndrome has many of the same symptoms as a traditional heart attack caused by a blocked artery. These traps have a round bottom with a narrow neck. The condition can also be triggered by a serious physical illness or surgery. Takotsubo cardiomyopathy, also called brokenheart syndrome, is a weakening of the left ventricle that is usually the result of severe stress. Women comprise 6070% of patients with chemotherapyassociated ts, a distinctly lower prevalence than the 90% female prevalence in ts overall.
A 68yearold female with a history of hypertension, hyper. Takotsubo cardiomyopathystressinduced cardiomyopathy 2. Takotsubo syndrome is a rare clinical condition, with a pathophysiology that is not fully understood. Stress cardiomyopathy also called apical ballooning syndrome, takotsubo cardiomyopathy, broken heart syndrome, and stressinduced cardiomyopathy is a syndrome characterized by transient regional systolic dysfunction of the left ventricle lv, mimicking myocardial infarction, but in the absence of angiographic evidence of obstructive coronary artery disease or acute plaque. The patient was diagnosed with takotsubo syndrome ts, discharged on betablockers, and seen 2 years later without any adverse events in between. The shape of the left ventricle during systole appeared to have similarities with japanese octopus trapping pots called takotsubo, which have round bottoms and narrow necks.
Several stressors have been identified to precede the onset of tts in a substantial proportion. Takotsubo cardiomyopathy is a weakening of the left ventricle, the hearts main pumping chamber, usually as the result of severe emotional or physical stress, such as a sudden illness, the loss of a loved one, a serious accident, or a natural disaster such as an earthquake. It is characterized by substantial morbidity and mortality, which equal. It is a temporary heart condition that shares many of the symptoms of a heart attack. For additional examples, see stressors associated with takotsubo. Recently, it was demonstrated that specific alterations in neurological response and. Patients with takotsubo cardiomyopathy had a higher prevalence of neurologic or psychiatric disorders than did those with an acute coronary syndrome. Phenomena noted for long time multivessel coronary artery spasm is a possibility dote k, sato h, tateishi h, uchida t, ishihara m. Takotsubo syndrome tts has been recognized for over 25 years. Midventricle takotsubo in a patient with goodpasture syndrome. In japanese takotsubo means a fishing pot for trapping octopus. Overview left ventricular apical akinesis octopus trap mimics acute coronary syndrome st elevation elevated troponin no coronary stenosis unknown etiology triggered by emotional stressor 3. An elderly woman, emotional stress, betablockers, and a good prognosisoverall, a transient benign disease.
International expert consensus document on takotsubo. Gianni m, dentali f, grandi am, et al eurheart j 2006. Mar 19, 2019 chemotherapy treatment of malignancy accounts for 12% of takotsubo syndrome ts triggers. Takotsubo syndrome underdiagnosed, underestimated, but understood. Electrocardiography ecg reveals st segment elevation or depression, t wave inversion and prolonged qtc interval.
Takotsubo cardiomyopathy, also known as transient apical ballooning syndrome, 1 apical ballooning cardiomyopathy, 2 stressinduced cardiomyopathy, brokenheart syndrome, and simply stress cardiomyopathy, is a type of nonischemic cardiomyopathy in which there is a sudden temporary weakening of the myocardium the muscle of the heart. Electrocardiography ecg reveals st segment elevation or depression, t wave inversion and. To report a case of takotsubo cardiomyopathy, also known as apical ballooning syndrome or stress cardiomyopathy. Electrocardiography ecg reveals st segment elevation or. This condition represents an acute heart failure syndrome with substantial morbidity and mortality.
Its symptoms resemble those of a heart attack, and treatment is usually the same as that for heart failure. This story represented the typical perception of ts at that time. Takotsubo syndrome tts is characterized by transient, regional systolic dysfunction of the left ventricle, often mimicking acute coronary syndrome. Chemotherapy treatment of malignancy accounts for 12% of takotsubo syndrome ts triggers. Sep, 2017 takotsubo syndrome ts is an acute reversible heart failure characterized by transient wall motion abnormality of left ventricle lv usually following a stressful event. Broken hearttakotsubo syndrome history medical news. Takotsubo syndrome tts is characterized by transient left ventricular lv dysfunction, typically mimicking an anterior wall myocardial infarction mi, without obstructive coronary artery disease. However, certain reports identifying presumed new entities such as apical ballooning syndrome, ampulla cardiomiopathy, broken heart syndrome characterised by nearly the same clinical features of tc have generated uncertainties concerning the nomenclature and debate is ongoin. Postoperative cardiogenic shock secondary to takotsubos syndrome. Apr 10, 2019 takotsubo syndrome tts is a transient form of acute heart failure that mimics an acute coronary syndrome acs, with comparable acute adverse outcome. Trigger factors in takotsubo syndrome a systematic. Takotsubo cardiomyopathy brokenheart syndrome harvard health. Jan 03, 2020 takotsubo syndrome tts, also known as takotsubo cardiomyopathy, is a transient left ventricular wall dysfunction that is often triggered by physical or emotional stressors.
Takotsubo syndrome tts is a recently identified cardiac disease, which is far from being completely known. It is characterized by substantial morbidity and mortality, which equal those of acute coronary syndromes acs and are still underappreciated 1. Takotsubo syndrome derived its name from the japanese word for octopus trap, due to the shape of the lv at the end of systole and has been described under a remarkable number of different names in the literature including broken heart syndrome, stress cardiomyopathy, and apical ballooning syndrome. Takotsubo syndrome tts, also known as brokenheart syndrome, apical ballooning syndrome or stress cardiomyopathy, is an emerging clinical syndrome characterized by acute left ventricular dysfunction that mimics an acute coronary syndrome in regard to clinical. Takotsubo syndrome tts is a poorly recognized heart disease that was initially regarded as a benign condition. Takotsubo syndrome is a relatively new condition first described in 1990 and knowledge is still limited. It is characterized by substantial morbidity and mortality, which equal those of acute coronary syndromes acs and are still underappreciated 11.
The term takotsubo cardiomyopathy was first used in japan in 1990 to describe this syndrome. An echocardiogram or a left ventriculogram resembles a takotsubo, a japanese octopus fishing pot. Takotsubo syndrome is named after a type of octopustrapping pot used by japanese fishermen tako octopus, tsubo pot. Takotsubo cardiomyopathy or takotsubo syndrome tts, also known as stress cardiomyopathy, is a type of nonischemic cardiomyopathy in which there is a sudden temporary weakening of the muscular portion of the heart. Although this disease is increasingly recognized, the true prevalence of tts is still underestimated and the disease course underappreciated. Recently, it has been shown that tts may be associated with severe clinical complications including death and that its prevalence is probably underestimated.
Abstract takotsubo syndrome is characterized by angina and st elevation simulating acute myocardial infarction and is distinguished by the. For the diagnosis of takotsubo syndrome to be possible, the absence of coronary artery disease as a cause is required. Le takotsubo, maladie du muscle cardiaque a ete decrit. International expert consensus document on takotsubo syndrome. Apical ballooning syndrome or takotsubo cardiomyopathy. Takotsubo syndrome tts is a transient form of acute heart failure that mimics an acute coronary syndrome acs, with comparable acute adverse outcome. It could be considered an acute heart failure syndrome where the left ventricle contracts abnormally without a corresponding coronary artery stenosis or plaque rupture. Sa physiopathologie reste incertaine et son traitement reste empirique. Originally described by sato et al 1 in the 1990s, takotsubo syndrome tts presents as an acute coronary syndrome acs characterized by severe left ventricular lv dysfunction that typically recovers spontaneously within days or weeks.
Extensive research over the last years has contributed to a better understanding of tts. Since then, many cases of seizure related tc have been reported 2, 26. We report a case of takotsubo syndrome in a 47yearold. Takotsubo syndrome in a premenopausal patient bmj case reports. Patient recovery is fast and not provide any prolonged health effect. It may also be called stress cardiomyopathy, takotsubo cardiomyopathy or apical ballooning syndrome. In the few published reports assessing myocardial deformation in tts and mi, no consistent differences have been described between the two entities. Unlike acute coronary syndrome, with an onset peak early in the morning, tcm presents in the afternoon in most cases when stressful inducible. Although tts is a rare disease with a prevalence of only 0.
Takotsubo syndrome ts is an acute reversible heart failure characterized by transient wall motion abnormality of left ventricle lv usually following a stressful event. Takotsubo cardiomyopathy, also known as transient apical ballooning syndrome, broken heart syndrome and transient left ventricular dysfunction syndrome, is a relatively recently described entity, first reported in 1990 and only recognized as an independent diagnostic entity in 2001, now classified among the stress cardiomyopathies. As per the data of international takotsubo registry which included 1750 patients with stress cardiomyopathy, 89. Epidemiology, pathogenesis, and management of takotsubo syndrome. Even though tts was generally considered a benign condition. Takotsubo cardiomyopathy brokenheart syndrome harvard. Recently, it was demonstrated that specific alterations in neurological response and sympathetic activation after emotional stimuli. The symptoms of takotsubo syndrome are same as heart attack, which includes chest pain, shortness of breathing 4. Takotsubo syndrome tts, also known as takotsubo cardiomyopathy, is a transient left ventricular wall dysfunction that is often triggered by physical or emotional stressors. Cependant, cette pathologie peut necessiter une reanimation. Takotsubo syndrome is reversible and temporary medical event, therefore it usually does not cause a fatal outcome. Myocardial stunning due to simultaneous multivessel coronary spasms. Ghadri, mda t akotsubo syndrome tts is an acute heart failure syndrome that predominantly affects postmenopausal women. Novel aspects of classification, prognosis and therapy in.
A diagnosis of tts can be made using mayo diagnostic criteria. Characterised by an acute and usually reversible heart failure, the condition is often preceded by a stressful event. Takotsubo is a name given to the syndrome by japanese medical professionals who noticed that some patients who presented at emergency rooms with the symptoms of a heart attack did not have blocked arteries. It is a temporary heart condition that shares many of. Postoperative cardiogenic shock secondary to takotsubos. Patients may present with abruptonset chest pain or dyspnea. Jun 28, 2018 takotsubo cardiomyopathy is also known as stress cardiomyopathy or broken heart syndrome. Nov 14, 2019 broken heart syndrome is a temporary heart condition thats often brought on by stressful situations and extreme emotions. Dysfonction ventriculaire gaucheetiologie stresscomplications.
Among patients with takotsubo cardiomyopathy, as compared with an acute coronary syndrome, rates of neurologic or psychiatric disorders were higher 55. Takotsubo cardiomyopathy tc or syndrome was first described more than 2 decades ago by dote and colleagues in japan, but has since been increasingly recognised around the world. Pdf the takotsubo syndrome is a reversible form of an acute stressrelated cardiomyopathythat was recently described. Broken heart syndrome symptoms and causes mayo clinic. Clinical features and outcomes of takotsubo stress. Takotsubo syndrome tts, also known as brokenheart syndrome, apical ballooning syndrome or stress cardiomyopathy, is an emerging clinical syndrome characterized by acute left ventricular dysfunction that mimics an. Takotsubo syndrome tts is an acute heart failure syndrome that predominantly affects postmenopausal women.
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